There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. That's the downside there. 7. These ASOs regulate the expression of a specific factor, which if present causes a particular disease. The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines. Many of today's most influential medicines, from the life-saving cancer treatment Keytruda to the anti-inflammatory agent Humira, might not have become so without mergers and acquisitions. The most recent update provided by the company suggests it may take several quarters for the issue to be resolved. To make the world smarter, happier, and richer. Scott is an independent investor/writer/trader and team leader of StockMatusow.com. Rumors. Alexion Pharma is no stranger to takeover rumors. Source: Mongkolchon Akesin / Shutterstock.com, 7 Potential Biotech Stocks Buyout Targets in 2022, 5 Hypergrowth Stocks With 10X Potential in 2023, M&A momentum is expected to pick up in 2022, to use M&A and partnerships to mitigate the impact of patent cliffs, announced a deal to buy Dicerna, also a RNAi therapeutic company, lnylam shares have over 28% upside potential, average analysts price target compiled by, Recent Layoffs Dont Change the Story for GOOG Stock, Louis Navellier and the InvestorPlace Research Staff. Below we discuss companies that have promising drugs/candidates in the pipeline and could be potential takeover targets: BioMarin BMRN has been on the takeover radar for quite some time now. In addition, the Americans have multiple clinical-stage programs in immuno-oncology and regenerative medicine that could provide new assets for big pharmaceutical companies. 12. Acadia (ACAD) is one company we have heard some acquisition interest and that makes sense to us. I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. Incyte has an attractive pharmaceutical portfolio comprising of Jakafi, a blockbuster drug for rare blood cancer indications, and 3 other marketed drugs, and a well-stocked pipeline. 1125 N. Charles St, Baltimore, MD 21201. *Stock Advisor returns as of September 17, 2021. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. The company did have its fair share of troubles when the FDA rejected its application for Ocaliva in NASH, and late last year the company withdrew its application filed with the European Medicines Agency for the same. Ionis (NASDAQ:IONS) is commercial-stage biopharma developing RNA-targeted therapy using antisense technology that can control gene expression in a cell using antisense oligonucleotides (ASO). Are some major acquisitions on the way in the biopharmaceutical industry this year? BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . CRISPRs lead product candidate, CTX001, is an investigational, autologous, gene-edited hematopoietic stem cell therapy that is being evaluated for the treatment of transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: Markets. All rights reserved. The rumor involved Pfizer (PFE) being the acquirer. Subscribe to BioPharma Dive. BioMarin is almost every analyst's favorite takeover candidate. Type a symbol or company name. Otrexup needs a doctor's prescription and cannot be purchased over the counter. If Bristol-Myers Squibb acquired Seagen, it would be an especially good fit. The Company submitted a Marketing Authorization Application to the. Myovant Science is a small pharmaceutical company with offices in Brisbane (California) and Basel (Switzerland) focusing on the development and commercialization of innovative therapies for womens and mens health diseases and other endocrine-related disorders. Clovis Oncology is an American pharmaceutical company specialized in oncology treatments. Go and get the Biotech Investments HOT STOCK REPORT. There were a few, but not as many. Price as of January 17, 2023, 4:00 p.m. It is focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Gene-editing company Crispr (NASDAQ:CRSP) has long been considered as a potential M&A target owing to its promising technology platform and its longstanding partnership with Vertex Pharma (NASDAQ:VRTX). RTTNews->. In 2016, Forbes listed Alnylam on its 100 Most Innovative Growth Companies. But there are some deals that Motley Fool contributors Brian Orelli and Keith Speights hope will happen. Sold Pharsight Corporation to Tripos International: Mr. Rosen served on the Board of Directors of Pharsight Corporation. 06-01-2023. The reason is that their deal is for an over the counter product that Pfizer has in its inventory. It expects to grow its revenues by 14% in the next fiscal year. AMAG Pharmaceuticals (Market Cap $0.7bn) US specialty firm AMAG Pharmaceuticals Inc. is viewed as an acquisition target for companies established in women's health - specifically Novartis AG - due to the potential of bremelanotide in hypoactive sexual desire disorder (HSDD). Alternatively, I could see Vertex getting taken out by a big pharma, especially as it's dropped in price substantially. Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. Written by As well Dan has 5 years trading futures, specializing in E-minis and Treasury products. Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. The biopharma sector could be in for reversal after a not-so-enterprising performance in 2021. (Source: EY 2019 M&A Firepower Report) 1. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. RTT's Financial Newswire is relied upon by some of the world's largest financial institutions, including banks, brokerages, trading platforms and financial exchanges. If you're going to give me a quick up-front profit, I'm definitely going to take it and I'm not going to complain about it. Mergers & Acquisitions (M&As) are back in focus in the biotech sector as Merck MRK recently acquired Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 . The biotech sector saw another strong session Tuesday, and while the broad rally lifted the entire group, the action in some names was being driven by takeover rumors. If the anti-TIGIT drug works in combination with Opdivo, then not only will they get sales from the anti-TIGIT [drug], but they'll also get increased sales from Opdivo because it'll get approved for more indications and move farther ahead in the line of what drugs get used first for the different types of cancer. . In 2003, Alnylam merged with the German pharmaceutical company, Ribopharma AG. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. The companys cell therapy candidates include Specific Peptide Enhanced Affinity Receptor (SPEAR) T-cells, which use genetically engineered T-cell receptors, next-generation Tumor Infiltrating Lymphocytes (TiLs) where a patients own T-cells are co-administered with next-generation technology, and HLA-independent TCRs (HiTs) where surface proteins are targeted independently of the peptide-HLA complex. ATRS. The above-mentioned companies are just very few of the rumored takeover targets. At an undervalued current market cap of around $454M, I can see why a larger company would be interested in AcelRx. Making the world smarter, happier, and richer. The first few months lived up to expectations: All of the top 10 M&A deals of January-June 2018 exceeded $1.5 billion, paced by the completion of Bayer's $63 billion buyout of Monsanto . Keep track of M&A as it happens with this database. Want the latest recommendations from Zacks Investment Research? Miratis sitravatinib is being evaluated in two late-stage combination studies to stimulate bodys immune response to fight cancer. The company's portfolio consists of a few commercialized products and multiple clinical and pre-clinical product candidates. Speights: Yeah. FTX Fooled the World. 4. 6. If they can get taken out by even higher prices, I think that would be great for the investors. Is this happening to you frequently? Shockwave Medical bolsters medical device portfolio with acquisition of Neovasc. To make the world smarter, happier, and richer. This year has seen a modest rebound after a slow start, and analysts believe a further resurgence is likely. Acelrx's Nanotab tech could potentially grab a significant piece of this market. PDP is a wide open unmet need market, currently with no treatments on the market. Copyright Clovis leading drug Rubraca (rucaparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, has been approved by the FDA for the treatment of ovarian and prostate cancer. In addition, the American company has several commercial and research successes, including recent positive Phase 3 clinical trial data for its ATTR amyloidosis drug ONPATTRO (Patisiran). Brian Orelli: I'd like to see Bristol-Myers Squibb (BMY -0.28%) acquire Seagen (SGEN -1.71%). Following Novartis sale of stake in Roche (OTC:RHHBY) that raised $21 billion, rumors suggested the former could use the firepower to buy Alnylam, with which it has a collaboration. Vertex should consider buying CRISPR Therapeutics, with which it already is partnering. Use a + to require a term in results and - to exclude terms. One of those stocks was. CRISPR Therapeutics CRSP is one of the leading gene-editing companies. His work with diagnostics development give him a strong background in immunology which is leveraged in evaluating immunology focused approaches. One of the catalysts that could work in its favor is deal optimism. I am not receiving compensation for it. Sold Kos Pharmaceuticals to Abbott Laboratories (ABT): Mr. Adams served as the President and Chief Executive Officer of Kos Pharmaceuticals, Inc. Abbott Laboratories bought out Kos Pharmaceuticals for $78 a share, or a 56% premium over the current share price. (2016). 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